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Brushing, fluoride, checkups: what you look after outside the clinic
Periodontitis Bacteria Found to Cross Into the Brain and Raise Alzheimer's Protein Levels
Researchers have confirmed a pathway by which bacteria that cause periodontitis cross the blood-brain barrier in mice and increase amyloid-beta, the protein hallmark of Alzheimer's disease. This article covers the process mediated by the immune protein IFITM3 and the current state of treatment development for humans.
3 min read
Ferroelectric Implant Surface Uses Ultrasound On/Off Switching to Sequence Bacterial Clearance and Bone Integration
A ferroelectric material coated onto titanium implants generates an electrical signal that clears bacteria when exposed to ultrasound, and a different electrical signal that promotes bone attachment when the ultrasound is turned off. This article explains the mechanism, confirmed in mouse experiments, and how it differs from existing antibacterial coatings.
4 min read
vVardis, Which Fixes Cavities Without a Drill, Pursues a US IPO
Swiss dental startup vVardis is preparing for a US stock listing, having retained JPMorgan Chase and Goldman Sachs as advisers. The news comes less than two months after Apollo Global Management's investment valued the company at $1 billion in April. This article looks at the strategy behind the listing and any links to South Korea.
2 min read
Shark Teeth Crack More Easily as the Ocean Grows More Acidic
Researchers at Heinrich Heine University Düsseldorf in Germany soaked more than 600 shark teeth in seawater matching today's acidity and the acidity projected for the year 2300. The more acidic water left the teeth cracked, pitted, and corroded down to the root. The article also covers experts' differing interpretations and the parallel with human dental erosion.
3 min read
For TMJ Osteoarthritis Injections, Stem Cell-Derived Therapy Outperformed Hyaluronic Acid
Intra-articular injections for temporomandibular joint (TMJ) osteoarthritis have expanded beyond hyaluronic acid alone to include platelet-rich plasma (PRP) and stem cell-derived therapies. A 2025 systematic review found that PRP performed similarly to hyaluronic acid, while stem cell-derived therapy showed better improvements in both pain and maximum mouth opening.
3 min read
Plasma-Activated Water Switches Between Killing Bacteria and Regrowing Vessels by Voltage in Peri-Implantitis
A research team at Nanjing Medical University in China created plasma-activated water by adjusting voltage between 33 and 46 kV, and confirmed in the lab that on implant surfaces, high voltage sharply reduces periodontitis-causing bacteria while low voltage promotes blood vessel regeneration. A single device may be able to switch between biofilm removal and vascular regeneration, the two core tasks in peri-implantitis treatment, though the evidence is still limited to cells and bacteria.
3 min read
Attack on Dubai-Bound Flight: A Dentist's First Aid Saved the Captain's Life
When a copilot stabbed the captain on a flight from Dubai to Israel, a passenger who happened to be a dentist stayed by the badly bleeding captain's side and helped save his life. With help from a plumber among the passengers and foreign pilots on board, the plane made an emergency landing in Saudi Arabia.
3 min read
Adding Ozone Gas to Periodontitis Scaling Shrank Pockets Further, but Bleeding Stayed the Same
In a split-mouth clinical trial comparing both sides of the mouth in 39 periodontitis patients, adding ozone gas to scaling produced greater improvement in pocket depth and attachment level, along with a sharp drop in anaerobic periodontal bacteria. However, there was no difference in bleeding or plaque, and the conclusions of accumulated meta-analyses remain mixed, so it is still too early to adopt ozone therapy as standard treatment.
4 min read
Tooth-Regrowth Drug Clears Phase 2 Review Hurdle in Japan
Japanese biotech venture Toregem BioPharma's tooth-regeneration antibody drug TRG035 has passed Japan's regulatory document review to begin a Phase 2 trial in children. We look at how the drug works by blocking the USAG-1 protein to wake up dormant tooth buds, the clinical progress so far, and what remains before commercialization.
2 min read
Bradesco Absorbs Dental Insurer Odontoprev to Build a $10 Billion Health Group
Brazil's largest bank, Bradesco, is using its dental insurance subsidiary Odontoprev as the surviving entity to build a healthcare group with roughly $10 billion in annual revenue, spanning hospitals and primary care clinics. It offers a different picture from Korea's fixed-benefit dental insurance products.
3 min read
Dyson's 750,000-Won AI Toothbrush Sold Out on Preorder Day in Korea, Then Vanished From US Stores Over a Defect
Dyson's 750,000-won AI toothbrush, the CameraJet, sold out on its first day of preorders in Korea, only to disappear from US stores soon after amid defect reports. Dyson has now said a component issue in one early production batch could let water seep into the device. Early Korean buyers aren't entirely in the clear either, though no domestic cases have surfaced so far.
3 min read
Medication-Related Osteonecrosis of the Jaw: Laser-Assisted Surgery Brought Fewer Complications and Better Recovery
A randomized controlled trial added an Er:YAG laser to surgery for medication-related osteonecrosis of the jaw, a side effect of drugs such as osteoporosis medications, and found large differences in complications and recovery. Here is what the laser does differently and how much evidence has accumulated so far.
3 min read
New in other areas
How Do You Choose Between an Onlay and a Crown for a Broken Molar?
- [Dental Q&A]If the Resin Filling a Small Front Tooth Comes Off, Do I Need to Switch to a Laminate?
- [Dental Q&A]What Treatment Do I Need If My Gums Hurt and a Tooth Feels Loose?
- [Dental Q&A]Does a Change in Crown Color or Gum Margin on a Front Tooth Mean It Needs Replacing?
- [Dental Q&A]Does a Baby Tooth Need a Crown After Root Canal Treatment?
- [Dental Q&A]How Are Resin, Inlay, and Crown Chosen for Cavity Treatment?